Slide scanner for FISH analysis


Product description

μSpots is a fluorescence slide scanner for FISH analysis and cytogenetic research using samples applied through micro-channels on dedicated Microfind® slides produced by Tethis S.p.a.

μSpots allow fast, flexible and reliable navigation, acquisition, analysis, archiving and transfer of high quality digital images.

This scanner can acquire images with low-emission fluorochromes thanks to the integrated highly sensitive monochrome camera. μSpots performs each process in a single working environment, guaranteeing optimized workflows tailored to suit the pathologist’s needs.

Its automatic revolving system offers a choice of 7 different objectives for a wide range of selectable magnifications.

The digital microscope allows real-time slide browsing and workflow control from remote workstations.

μSpots is a valuable support for target therapy as well thanks to its dedicated FISH analysis modules: BCR/ABL, FISH spot counting for detection of DiGeorge syndrome, Patau syndrome, Down syndrome, XX/XY anomalies, AneuVysion test, and other prenatal diagnostic tests.

The highly sensitive monochrome camera can quickly acquire a composition of several focal planes per channel for each field, allowing reconstruction of the highest quality color FISH image. Each channel can be managed independently, turning channels on and off, using a pseudocolor representation and viewing the focus change for each field in z-stack through the virtual microscope.

A sophisticated algorithm and image processing system provides very accurate detection of nuclei and spots for the classification and scoring of digital slides. All detected nuclei can be reviewed in a classification gallery. With its dedicated Web application, μSpots assures remote unlimited access to acquired images and password-protected access to individual files and working environments.

μSpots has a dedicated joystick – ENJOY – designed for both right and left hand use. it allows to move along the X and Y axes with the same ease as a normal microscope. Zoom, one touch image reduction and enlargement, X, Y navigation, magnification and navigation speed can be fully controlled through ENJOY.

Hardware specifications

4x, 20x, 60x Oil immersion

Scanning speed
Few minutes for several hundred cells

5 slides

Multi position filter cubes
Up to 6 channels

Software specifications

  • Complete database management
  • Automated scanning procedure
  • Z-stack acquisition for FISH analysis
  • Quantitative image analysis for FISH